Category:SEA

SEA, the Similarity Ensemble Approach. The website is: sea.bkslab.org

About

SEA relates proteins based on the set-wise chemical similarity among their ligands. It can be used to rapidly search large compound databases and to build cross-target similarity maps.

Citing SEA

To cite SEA, please reference Keiser MJ, Roth BL, Armbruster BN, Ernsberger P, Irwin JJ, Shoichet BK. Relating protein pharmacology by ligand chemistry. Nat Biotech 25 (2), 197-206 (2007).^[1]

Publications

Using the SEA website

Obtaining a private copy of SEA

Other topics

• Install SEA

• Generate model

• Basic Tutorial

• Chembl processing protocol

References