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Why did we create ZINC22?

ZINC15/20 had reached a limitation in design that prevented us from growing the database rapidly. ZINC22 is a federation of databases that allows concurrent loading, numbering, and handling, removing the central bottleneck to database growth. ZINC22 is designed to be built at multiple sites and federated into a single database. This design allows ZINC22 to grow at the rate of billions of molecules per year.