Difference between revisions of "Targets"

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Targets for ligand discovery can be [[enzymes]], [[receptors]], or [[protein-protein surfaces]], although these are very challenging for small molecules due to the lack of deep invaginations that are usually required for tight small molecule binding.
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Targets for ligand discovery can be [[enzymes]], [[receptors]], or [[protein-protein surfaces]], although these are very challenging for small molecules due to the lack of deep invaginations that are usually required for tight small molecule binding. [[Allosteric sites]] on each of the above are also possible targets, in principle.

Revision as of 21:18, 30 November 2007

Targets for ligand discovery can be enzymes, receptors, or protein-protein surfaces, although these are very challenging for small molecules due to the lack of deep invaginations that are usually required for tight small molecule binding. Allosteric sites on each of the above are also possible targets, in principle.