Psicquic channels

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Target-Target Channels

  • 1. Sea prediction (T-T)
  • 2. blast similarity (Evalue)
  • 3. co-expression data from Matt (100 to 0 percentile rank)
  • 4. shared ligand, 1uM or better
  • 5. PPI (biogrid, experimental)

Target-Compound Channels

  • 1. Experimental binder, is bioactive and binds 1uM or better per chembl20
  • 2. is a drug and binds target 10uM or better
  • 3. Is biogenic and binding 1uM or better
  • 4. is and endogenous metabolite for this target
  • 5. SEA prediction (TC, P-value)