DOCK Blaster:50826

I have done re-docking of GIG303 inhibitor in its native 3D protein taken from PDB: 2OH4. Its newly assigned position in protein after re-docking has been not correct (result after superimposition of 2OH4 and re-docked GIG303). The problem could be in activation loop that prevents the right positioning of its native inhibitor. Probably the activation loop has low flexibility by dynamic re-docking or the problem could be in not right assignment of inhibiting environment because GIG303 is accompanied by two sulfates forming its better soluble salt. Andrej