Are critical points/spheres supported in my version of DOCK?
DOCK FAQ: Are critical points/spheres supported in DOCK 4, 5, 6?
Yes, critical points/spheres are supported in all versions of DOCK. Try using automated matching if manual matching seems not to work
Note that the final conformations for the critical matching may indeed be some distance away from the critical points if you are minimizing during your run depending on whether the molecules can fit in the area of the active site you have defined as critical.
For more information on labeling spheres, go to the DOCK 6 manual on our web site at dock.compbio.ucsf.edu under Sphgen >> Output.
Credit: Terry Lang