Asthma

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Therapeutic targets for Asthma

  • acidic mammalian chitinase (AMCase)

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  • Interleukin-5 and eosinophils

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  • adenosine receptors

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  • Calcium sensors

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  • Immunoglobulin E (IgE)

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  • interleukin-9

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  • Eotaxin and CCR3

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  • Interleukin-4 and Interleukin-13

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  • Toll-like receptors

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  • US patents, 2000-2004 (from Zheng, Pharmaceutical Sci. 2006

{alpha}2-Adrenergic receptor beta-Adrenergic receptor Substance P receptor (39) Cyclooxygenase 2 (38) Adenosine A1 receptor Adenosine A2b receptor Endothelin A receptor Endothelin B receptor 5-Lipoxygenase (8) Serine protease (7) IL-1R-a

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