Asthma

Therapeutic targets for Asthma.

Unknown

• acidic mammalian chitinase (AMCase)

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• Interleukin-5 and eosinophils

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• adenosine receptors

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• Calcium sensors

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• Immunoglobulin E (IgE)

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• interleukin-9

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• Eotaxin and CCR3

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• Interleukin-4 and Interleukin-13

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• Toll-like receptors

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• US patents, 2000-2004 (from Zheng, Pharmaceutical Sci. 2006

{alpha}2-Adrenergic receptor beta-Adrenergic receptor Substance P receptor (39) Cyclooxygenase 2 (38) Adenosine A1 receptor Adenosine A2b receptor Endothelin A receptor Endothelin B receptor 5-Lipoxygenase (8) Serine protease (7) IL-1R-a