http://wiki.docking.org/index.php?action=history&feed=atom&title=Best_database_to_screen 2026-04-04T19:08:51Z Revision history for this page on the wiki MediaWiki 1.39.1 http://wiki.docking.org/index.php?title=Best_database_to_screen&diff=7493&oldid=prev 2014-03-21T16:34:21Z

<p>Created page with &quot;People want to know, what is the best database to screen and the best technique to screen it? The answer depends on various circumstances, which we take up in turn: &#039;&#039;&#039;NB t...&quot;</p> <p><b>New page</b></p><div>People want to know, what is the best database to screen and the best technique to screen it? The answer depends on various circumstances, which we take up in turn: <br /> <br /> &#039;&#039;&#039;NB this is work in progress&#039;&#039;&#039;<br /> <br /> = Experimental screen = <br /> <br /> == Direct biophysical observation ==<br /> <br /> * Xray, NMR, SPR<br /> <br /> == Inferential endpoint? ==<br /> <br /> * spectrophotometric, HTS<br /> === <br /> <br /> <br /> <br /> = virtual screen followed by cherry picked testing ? = <br /> <br /> <br /> * Can wait 10 weeks vs ASAP (2 weeks)<br /> * Fragment or Leads? <br /> * Phenotypic or ligand discovery? <br /> * known ligands? analogs OK? <br /> * size of binding site<br /> * affinity needed? <br /> <br /> <br /> <br /> [[Category:FAQ]]</div>

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