Which genes do what?: Difference between revisions

From DISI
Jump to navigation Jump to search
(asdf)
 
(asdf)
Line 3: Line 3:


How about for one particular gene, say, CA1:  
How about for one particular gene, say, CA1:  
<pre>
  http://zinc15.docking.org/genes/CA1/substances/?substance.structure-contains=C4=C1CCCCC1[C@H]3CCC2CCC[C@H]2[C@@H]3C4
  http://zinc15.docking.org/genes/CA1/substances/?substance.structure-contains=C4=C1CCCCC1[C@H]3CCC2CCC[C@H]2[C@@H]3C4
</pre>


Which genes bind one or more bitter compounds in bitterdb?  
Which genes bind one or more bitter compounds in bitterdb?  
Line 12: Line 14:


Which genes bind one or more FDA approved drugs at 100nM or better?
Which genes bind one or more FDA approved drugs at 100nM or better?
<pre>
  http://zinc15.docking.org/genes/?substance.features-contains=210&observation.affinity-ge=7
  http://zinc15.docking.org/genes/?substance.features-contains=210&observation.affinity-ge=7
</pre>


How about for one individual gene, say, DRD2:
How about for one individual gene, say, DRD2:
 
<pre>
http://zinc15.docking.org/genes/DRD2/substances?substance.features-contains=210&observation.affinity-ge=7
http://zinc15.docking.org/genes/DRD2/substances?substance.features-contains=210&observation.affinity-ge=7
</pre>


Which genes can I get ligands tested for using a CRO?  
Which genes can I get ligands tested for using a CRO?  

Revision as of 16:19, 8 July 2015

Which genes bind sterols?

http://zinc15.docking.org/genes?substance.structure-contains=C4=C1CCCCC1[C@H]3CCC2CCC[C@H]2[C@@H]3C4

How about for one particular gene, say, CA1:

 http://zinc15.docking.org/genes/CA1/substances/?substance.structure-contains=C4=C1CCCCC1[C@H]3CCC2CCC[C@H]2[C@@H]3C4

Which genes bind one or more bitter compounds in bitterdb?

http://zinc15.docking.org/genes?catalog.short_name=bitterdb

To see the ligands for one individual gene, say ABCC4, use: http://zinc15.docking.org/genes/ABCC4/substances?catalog.short_name=bitterdb

Which genes bind one or more FDA approved drugs at 100nM or better?

 http://zinc15.docking.org/genes/?substance.features-contains=210&observation.affinity-ge=7

How about for one individual gene, say, DRD2:

http://zinc15.docking.org/genes/DRD2/substances?substance.features-contains=210&observation.affinity-ge=7

Which genes can I get ligands tested for using a CRO?

Stay tuned.