Contract Research Organizations
Contract research organizations are companies that will perform specific in vitro and in vivo assays to testing the activity of compounds or therapies. Listed here are companies that the Shoichet lab has either worked with or considered working with in the past.
The NIMH Psychoactive Drug Screening Program run by the Roth lab at UNC Chapel Hill, has been a close collaborator in performing in vitro binding and functional assays for almost all GPCR targets and and several transporters. If the PDSP has the assay, they are typically our first choice.
Located in Taiwan, they have 1,350 assays covering the following target classes
- Cytokine/Chemokine (41)
- GPCR (270)
- Ion Channel (41)
- Kinase (154)
- Nuclear Receptor (16)
- Other (15)
- Phosphatase (31)
- Phosphodiesterase (19)
- Protease (51)
- Transporter (19)
They were used by both Henry Lin and Matthew O'Meara (2013-2014) and they gave reasonable results at reasonable prices.