Bioisosteres

The bioisostere tool is available at n-9-38:5000 and is currently in development. When it is ready for production it will appear at bioisostere.docking.org

Table of bioisosteric replacements.

other methods

http://www.swissbioisostere.ch/ - online tool

Accompanying paper https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3531158/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3531158/pdf/gks1059.pdf